Dr. Mack conducts basic, translational and clinical research in lung cancer, with an emphasis on liquid biopsies.  Dr. Mack joined the team at the Mount Sinai Tisch Cancer Institute in 2019 to serve as Associate Director of Translational Medicine for the Center for Thoracic Oncology. Recent work has included the creation, development and analysis of a large, longitudinal clinical study investigating the intersection between SARS-CoV-2 and lung cancer. Previously, Dr. Mack served as Director of the UC Davis Cancer Center Molecular Pharmacology Resource, Director of Basic Sciences for the California Cancer Consortium. He continues his role as Associate Director of the Southwest Oncology Group Lung Translational Medicine Committee. He specializes in preclinical modeling of novel cancer therapeutic regimens, clinical trial development, helped pioneer the concept of detecting circulating tumor DNA in patient plasma as an advanced diagnostic to enable precision medicine in oncology. He has over 120 peer-reviewed publications in oncology.